Our research efforts center on integrating innovative engineering, materials science, and cell biology concepts and technologies to generate (1) novel insights into the regulation of adhesive forces and mechanotransduction, and (2) cell-instructive adhesive materials for tissue repair in regenerative medicine applications. This cross-disciplinary effort, driven by the mantra "integration, innovation, and translation," will result in a new mechanistic understanding of the interplay of mechanics and cell biology and disruptive technologies and materials for regenerative medicine.